Some of the initiatives – which will be delivered by the voluntary, statutory and independent sectors – are aimed at improving the health and well-being of the whole population.
Others focus on reducing health inequalities and target those who are most disadvantaged.
They include those who are mentally ill, young people between the ages of 16 and 26, older people, low income households and those living in areas of severe disadvantage.
In all it is hoped that over 40,000 adults and children will benefit from the schemes.
Kerry McQuade, Project Manager for the North East Well-being Programme, said: "The projects present a real opportunity for the region to benefit from improvements in mental health and prevention of disease associated with poor diet and physical inactivity.
"The portfolio reflects the significant challenges of improving health and well-being in the region.
"All the partners involved are excited about the beginning of the programme and are looking forward to offering new and enhanced services to the region’s residents.”
